Researchers from Tufts University in the US presented recent findings that support the hypothesis that Alzheimer’s disease may be caused by a virus. The strain in question is very common because it is varicella zoster virus (VZV)
Announced nearly 225,000 people in France Every year, after the age of 65. Although this type of dementia is common, its origin is still hotly debated among specialists. There are all the same points of consensus: amyloid plaques and clusters in the structure of neurons
Each neuron consists of:
a cell body or pericarion containing the nucleus; Too many dendrites of the dendritic type (hence…”data-image=”data-url=”data-more=”read more”> involved in the onset of symptoms typical of Alzheimer’s disease, and that handles the function of the brain
The brain is located in the cranial box, which is the seat of higher functions (cognitive functions, senses, neurological responses) and vegetative functions. So it is an essential device that ensures that all… “data-image =” data-url = “data-more =” read more “> This toxicity is also dependent on the dose of the xenbiotic needed for… “data-image=”data-url=”data-more=”read more”> .
To explain these notes, . factors It appears to have an important role in sporadic cases of Alzheimer’s disease, the most common, but a defect in the synthesis of amyloid proteins or interference with this term includes a variety of very different species, whether prokaryotes (bacteria) or eukaryotes (yeast, algae). … “data-image =” data-url = “data-more =” read more “> Most of the time a virus can have an underlying effect.
Experiments in the laboratory on cultured neurons
A team from Tufts University in the US presented findings that fall within the “viral hypothesis” about the origin of Alzheimer’s disease. The latter states that there is a virus
Like all viruses of the family Herpesviridae and more specifically of the genus Varicellovirus, the … “data-image=”data-url=”data-more=”read more”> It causes inflammation that awakens HSV-1 in the brain Dana Kern explains Jobs
Cairns are used to mark tracks in arid and rocky areas or on glaciers. They can… “data-image =” data-url =” data-more =” read more “> the first author of.
To confirm this hypothesis, they infectedHuman neurons were labeled with viruses and looked for signs specific to Alzheimer’s disease: amyloid plaques and tau clumps, glia (proliferation in the brain) and neuritis. Their results show that VZV alone does not cause the formation of amyloid plaques and tau clumps, like HSV-1, but rather causes neuroinflammation and glia. This, according to scientists, indicates an indirect action of the VZV virus. In addition, they note that infection of cells, in which HSV-1 is dormant, by VZV reactivates the latter and causes changes typical of Alzheimer’s disease. ” It’s a double whammy from two very common and generally harmless viruses, but lab studies suggest that if additional exposure to VZV awakens dormant HSV-1, it can cause problems. Dana Kearns says.
These experiments alone are not strong enough to confirm a causal relationship between Alzheimer’s disease and VZV and HSV-1 viruses, even if the observations point in this direction. Moreover, the various hypotheses being studied about the origin of Alzheimer’s disease are not necessarily conflicting. Viral infection could be a factor to consider in Alzheimer’s disease, among other things.
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